Effect of signal peptide on stability and folding of Escherichia coli thioredoxin.

Effect of signal peptide on stability and folding of Escherichia coli thioredoxin.

The signal peptide plays a key role in targeting and membrane insertion of secretory and membrane proteins in both prokaryotes and eukaryotes. In E. coli, recombinant proteins can be targeted to the periplasmic space by fusing naturally occurring signal sequences to their N-terminus. The model prote...

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Bibliographic Details
Main Authors: Pranveer Singh, Likhesh Sharma, S Rajendra Kulothungan, Bharat V Adkar, Ravindra Singh Prajapati, P Shaik Syed Ali, Beena Krishnan, Raghavan Varadarajan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646739?pdf=render

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http://europepmc.org/articles/PMC3646739?pdf=render

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