The N‐terminal domains of the paralogous HycE and NuoCD govern assembly of the respective formate hydrogenlyase and NADH dehydrogenase complexes

Formate hydrogenlyase (FHL) is the main hydrogen‐producing enzyme complex in enterobacteria. It converts formate to CO2 and H2 via a formate dehydrogenase and a [NiFe]‐hydrogenase. FHL and complex I are evolutionarily related and share a common core architecture. However, complex I catalyses the fun...

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Bibliographic Details
Main Authors: Philipp Skorupa, Ute Lindenstrauß, Sabrina Burschel, Christian Blumenscheit, Thorsten Friedrich, Constanze Pinske
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12787