Cordycepin regulates GSK-3β/β-catenin signaling in human leukemia cells.

Leukemia stem cells (LSCs) are a limitless cell source for the initiation and maintenance of leukemia. Activation of the Wnt/β-catenin pathway is required for the survival and development of LSCs. Therefore, targeting β-catenin is considered a therapeutic strategy for the treatment of leukemia. The...

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Bibliographic Details
Main Authors: Bor-Sheng Ko, Yi-Jhu Lu, Wen-Ling Yao, Tzu-An Liu, Shean-Shong Tzean, Tang-Long Shen, Jun-Yang Liou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3784440?pdf=render