Activated protein C has a protective effect against myocardial I/R injury by improvement of endothelial function and activation of AKT1.
OBJECTIVES: Activated protein C (APC) has a protective efficacy against ischemia-reperfusion (I/R) injury in several organs. The objective of this study was to investigate effect of APC in myocardium with possible mechanism. METHODS: We used regional and global myocardial I/R injury models of rats....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3423409?pdf=render |