Imbalance between Th17 and regulatory T-cells in systemic lupus erythematosus

Imbalance between Th17 and regulatory T-cells in systemic lupus erythematosus

Impaired function of regulatory T-cells (Treg) leads to a failure in immune tolerance and triggers autoimmunity. We analyzed whether the deficiency in Treg in systemic lupus erythematosus (SLE) is accompanied by an increase in effector T-cell responses. We studied the frequencies of IL-17A (Th17) an...

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Bibliographic Details
Main Authors: Jacek Musial, Marek Sanak, Mamert Milewski, Hanna Plutecka, Bogdan Jakiela, Weronika Kleczynska
Format: Article
Language:English
Published: Via Medica 2012-01-01
Series:Folia Histochemica et Cytobiologica
Subjects:
systemic lupus erythematosus
regulatory T-cells
Th17 cells
Th1 cells
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/14724

Internet

http://czasopisma.viamedica.pl/fhc/article/view/14724

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