Imbalance between Th17 and regulatory T-cells in systemic lupus erythematosus
Impaired function of regulatory T-cells (Treg) leads to a failure in immune tolerance and triggers autoimmunity. We analyzed whether the deficiency in Treg in systemic lupus erythematosus (SLE) is accompanied by an increase in effector T-cell responses. We studied the frequencies of IL-17A (Th17) an...
Main Authors: | Jacek Musial, Marek Sanak, Mamert Milewski, Hanna Plutecka, Bogdan Jakiela, Weronika Kleczynska |
---|---|
Format: | Article |
Language: | English |
Published: |
Via Medica
2012-01-01
|
Series: | Folia Histochemica et Cytobiologica |
Subjects: | |
Online Access: | http://czasopisma.viamedica.pl/fhc/article/view/14724 |
Similar Items
-
A unique thymus-derived regulatory T cell subset associated with systemic lupus erythematosus
by: Hironari Hanaoka, et al.
Published: (2020-04-01) -
Peripheral blood Th17/Treg imbalance in patients with low-active systemic lupus erythematosus
by: Magdalena Szmyrka-Kaczmarek, et al.
Published: (2014-01-01) -
CD4+CD25+LAG3+ T Cells With a Feature of Th17 Cells Associated With Systemic Lupus Erythematosus Disease Activity
by: Rika Kato, et al.
Published: (2019-07-01) -
Hydroxychloroquine decreases Th17-related cytokines in systemic lupus erythematosus and rheumatoid arthritis patients
by: Juliana Cruz da Silva, et al.
Published: (2013-06-01) -
Disturbed T cell signaling and altered Th17 and regulatory T cell subsets in the pathogenesis of systemic lupus erythematosus
by: Nils eRother, et al.
Published: (2015-11-01)