Persistence of intrahepatic hepatitis B virus DNA integration in patients developing hepatocellular carcinoma after hepatitis B surface antigen seroclearance

Persistence of intrahepatic hepatitis B virus DNA integration in patients developing hepatocellular carcinoma after hepatitis B surface antigen seroclearance

Background/Aims The role of hepatitis B virus (HBV) integration into the host genome in hepatocarcinogenesis following hepatitis B surface antigen (HBsAg) seroclearance remains unknown. Our study aimed to investigate and characterize HBV integration events in chronic hepatitis B (CHB) patients who d...

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Bibliographic Details
Main Authors: Jeong Won Jang, Jin Seoub Kim, Hye Seon Kim, Kwon Yong Tak, Heechul Nam, Pil Soo Sung, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Lewis R. Roberts
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2021-01-01
Series:Clinical and Molecular Hepatology
Subjects:
hepatitis b virus
virus integration
liver neoplasms
hepatitis b surface antigens
population surveillance
Online Access:http://e-cmh.org/upload/pdf/cmh-2020-0115.pdf

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http://e-cmh.org/upload/pdf/cmh-2020-0115.pdf

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