Natural Autoimmunity to the Thyroid Hormone Monocarboxylate Transporters MCT8 and MCT10

Natural Autoimmunity to the Thyroid Hormone Monocarboxylate Transporters MCT8 and MCT10

The monocarboxylate transporters 8 (MCT8) and 10 (MCT10) are important for thyroid hormone (TH) uptake and signaling. Reduced TH activity is associated with impaired development, weight gain and discomfort. We hypothesized that autoantibodies (aAb) to MCT8 or MCT10 are prevalent in thyroid disease a...

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Bibliographic Details
Main Authors: Theresa Porst, Jörg Johannes, Hans Gluschke, Richard Köhler, Sebastian Mehl, Peter Kühnen, Kostja Renko, Waldemar B. Minich, Susanna Wiegand, Lutz Schomburg
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
thyroid hormone
transport
thyroid axis
autoimmunity
Online Access:https://www.mdpi.com/2227-9059/9/5/496

Internet

https://www.mdpi.com/2227-9059/9/5/496

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