Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens

Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens

The human Vγ9Vδ2 T cell is a unique cell type that holds great potential in immunotherapy of cancer. In particular, the therapeutic potential of this cell type in adoptive cell therapy (ACT) has gained interest. In this regard optimization of in vitro expansion methods and functional characterizatio...

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Bibliographic Details
Main Authors: Gitte Holmen Olofsson, Manja Idorn, Ana Micaela Carnaz Simões, Pia Aehnlich, Signe Koggersbøl Skadborg, Elfriede Noessner, Reno Debets, Bernhard Moser, Özcan Met, Per thor Straten
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
γδ or gamma delta T cells
Vγ9Vδ2 T cells
APC or antigen presenting cells
antigen cross-presentation
cancer
cancer killing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.645131/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.645131/full

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