Purification of pancreatic endocrine subsets reveals increased iron metabolism in beta cells

Objectives: The main endocrine cell types in pancreatic islets are alpha, beta, and delta cells. Although these cell types have distinct roles in the regulation of glucose homeostasis, inadequate purification methods preclude the study of cell type-specific effects. We developed a reliable approach...

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Bibliographic Details
Main Authors: C. Berthault, W. Staels, R. Scharfmann
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301344