The Amount of BCL6 in B Cells Shortly after Antigen Engagement Determines Their Representation in Subsequent Germinal Centers

Summary: It is unknown whether the incremental increases in BCL6 amounts in antigen-activated B cells influence the unfolding differentiation before germinal center (GC) formation. By comparing shortly after immunization the distribution of conventional B cells to those enforced to express BCL6 at t...

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Bibliographic Details
Main Authors: Marcus James Robinson, Zhoujie Ding, Catherine Pitt, Erica Janet Brodie, Isaak Quast, David Mathew Tarlinton, Dimitra Zotos
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720300188