Interleukin-10 Producing Regulatory B Cells Transformed CD4+CD25− Into Tregs and Enhanced Regulatory T Cells Function in Human Leprosy

Interleukin-10 Producing Regulatory B Cells Transformed CD4+CD25− Into Tregs and Enhanced Regulatory T Cells Function in Human Leprosy

Regulatory B cells (Bregs) are known to exhibit their regulatory functions through interleukin-10 (IL-10) cytokine which suppress inflammation. There are only a few studies explaining the phenotype and functioning of these cells in contribution to host immunity in leprosy. Here, we evaluated the rol...

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Bibliographic Details
Main Authors: Mohd. Tarique, Huma Naz, Santosh V. Kurra, Chaman Saini, Raza Ali Naqvi, Reeta Rai, Mohd Suhail, Neena Khanna, Donthamshetty N. Rao, Alpana Sharma
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
leprosy
regulatory B cells
Tregs
interleukin-10
FoxP3
Teff cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01636/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01636/full

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