Targeting cell cycle proteins in breast cancer cells with siRNA by using lipid-substituted polyethylenimines

Targeting cell cycle proteins in breast cancer cells with siRNA by using lipid-substituted polyethylenimines

The cell cycle proteins are key regulators of cell cycle progression whose de-regulation is one of the causes of breast cancer. RNA interference (RNAi) is an endogenous mechanism to regulate gene expression and it could serve as the basis of regulating aberrant proteins including cell cycle proteins...

Full description

Bibliographic Details
Main Authors: Manoj eParmar, Hamid M. Aliabadi, Parvin eMahdipoor, Cezary eKucharski, Robert eMaranchuk, Judith C Hugh, Hasan eUludag
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
RAD51
Xenograft
cdc20
siRNA therapy
Breast cancer therapy
CHEK1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00014/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00014/full

Similar Items