DNA Methylation in exon 1 of CDKN2A gene in formalin-fixed, paraffin-embedded colon cancer samples

Background: The molecular studies indicate some of the genes in the promoter region itself, will undergo methylation. Methylation of CpG islands in the promoter region of that cause silence or reduced expression of genes involved in cell growth pathways, which are colorectal cancer causing agents. D...

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Bibliographic Details
Main Authors: Hossein Faramarzi, Elham Moslemi, Amir Izadi
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2015-04-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5310&slc_lang=en&sid=1