Simulated Microgravity Promotes Angiogenesis through RhoA-Dependent Rearrangement of the Actin Cytoskeleton

Simulated Microgravity Promotes Angiogenesis through RhoA-Dependent Rearrangement of the Actin Cytoskeleton

Background/aims: Microgravity leads to hydrodynamic alterations in the cardiovascular system and is associated with increased angiogenesis, an important aspect of endothelial cell behavior to initiate new vessel growth. Given the critical role of Rho GTPase-dependent cytoskeleton rearrangement in ce...

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Bibliographic Details
Main Authors: Fei Shi, Yong-Chun Wang, Ze-Bing Hu, Hong-Yu Xu, Jing Sun, Yuan Gao, Xiao-tao Li, Chang-Bin Yang, Chao Xie, Cheng-Fei Li, Shu Zhang, Jiang-Dong Zhao, Xin-Sheng Cao, Xi-Qing Sun
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Simulated microgravity
Angiogenesis
Rho GTPase
Cytoskeleton dynamics
Migration
Online Access:http://www.karger.com/Article/FullText/456060

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http://www.karger.com/Article/FullText/456060

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