Extracellular Monomeric Tau Is Internalized by Astrocytes

Tau is a microtubule-associated protein that is expressed in neurons. However, in a group of neurodegenerative diseases named tauopathies – characterized by an increase in aggregated and/or hyperphosphorylated Tau – the protein accumulates inside other cells, such as astrocytes and microglia. Given...

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Bibliographic Details
Main Authors: Juan Ramón Perea, Esther López, José Carlos Díez-Ballesteros, Jesús Ávila, Félix Hernández, Marta Bolós
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Neuroscience
Subjects:
Tau
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00442/full