A stratification method based on clustering for the minimization of data masking effect in signal detection

Abstract Background Data masking is an inborn defect of measures of disproportionality in adverse drug reactions (ADRs) signal detection. Many previous studies can be roughly classified into three categories: data removal, regression and stratification. However, frequency differences of adverse drug...

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Bibliographic Details
Main Authors: Jian-Xiang Wei, Yue Ding, Ming Li, Jun Sun
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Medical Informatics and Decision Making
Subjects:
Online Access:https://doi.org/10.1186/s12911-020-1037-z