ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-I

ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-I

Prior studies provide data supporting the notion that ATP binding cassette transporter A1 (ABCA1) promotes lipid efflux to extracellular acceptors in a two-step process: first, ABCA1 mediates phospholipid efflux to an apolipoprotein, and second, this apolipoprotein-phospholipid complex accepts free...

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Bibliographic Details
Main Authors: Jonathan D. Smith, Wilfried Le Goff, Megan Settle, Gregory Brubaker, Christine Waelde, Andrew Horwitz, Michael N. Oda
Format: Article
Language:English
Published: Elsevier 2004-04-01
Series:Journal of Lipid Research
Subjects:
lipid efflux
ATP binding cassette transporter A1
Tangier disease
reverse cholesterol transport
endocytosis
cyclodextrin
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318472

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http://www.sciencedirect.com/science/article/pii/S0022227520318472

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