Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors

Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors

Abstract Background Neuraminidase (NA) is a sialidase present, among various locations, in the envelope/membrane of some bacteria/viruses (e.g., influenza virus), and is involved in infectiveness and/or dispersion. The administration of NA within the brain lateral ventricle represents a model of acu...

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Bibliographic Details
Main Authors: María del Mar Fernández-Arjona, Jesús M. Grondona, Pedro Fernández-Llebrez, María Dolores López-Ávalos
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Neuroinflammation
Subjects:
TLR2
TLR4
Neuraminidase
Microglia
Neuroinflammation
Oseltamivir
Online Access:https://doi.org/10.1186/s12974-019-1643-9

Internet

https://doi.org/10.1186/s12974-019-1643-9

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