The Streptococcus sanguinis competence regulon is not required for infective endocarditis virulence in a rabbit model.

Streptococcus sanguinis is an important component of dental plaque and a leading cause of infective endocarditis. Genetic competence in S. sanguinis requires a quorum sensing system encoded by the early comCDE genes, as well as late genes controlled by the alternative sigma factor, ComX. Previous st...

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Bibliographic Details
Main Authors: Jill E Callahan, Cindy L Munro, Todd Kitten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3198404?pdf=render