Randomised clinical trial for the cost–utility evaluation of two strategies of perineal reconstruction after abdominoperineal resection in the context of anorectal carcinoma: biological mesh repair versus primary perineal wound closure, study protocol for the GRECCAR 9 Study

Introduction Abdominoperineal resections performed for anorectal tumours leave a large pelvic and perineal defect causing a high rate of morbidity of the perineal wound (40%–60%). Biological meshes offer possibilities for new standards of perineal wound reconstruction. Perineal fillings with biologi...

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Main Authors: Jeremie Lefevre, Eddy Cotte, Nicolas Carrere, Arnaud Alves, Jean-Marc Regimbeau, Anne Dubois, Adeline Germain, Sylvain Kirzin, Etienne Buscail, Cindy Canivet, Laurent Ghouti, Laurent Molinier, Aline Rosillo, Valerie Lauwers-Cances, Nadège Costa, Aurélien Vénara, Zaher Lakkis, Eric Rullier, Guillaue Piessen, Bertrand Trilling, Cécilia Ceribelli, Cécile de Chaisemartin, Emilie Duchalais, Mehrdad Jafari, Jean-Jacques Tuech
Format: Article
Language:English
Published: BMJ Publishing Group 2021-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/4/e043333.full