Chloroquine analogs as antimalarial candidates with potent in vitro and in vivo activity

In spite of recent efforts to eradicate malaria in the world, this parasitic disease is still considered a major public health problem, with a total of 216 million cases of malaria and 445,000 deaths in 2016. Artemisinin-based combination therapies remain effective in most parts of the world, but re...

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Bibliographic Details
Main Authors: Anna C.C. Aguiar, Erika Murce, Wilian A. Cortopassi, Andre S. Pimentel, Maria M.F.S. Almeida, Daniele C.S. Barros, Jéssica S. Guedes, Mario R. Meneghetti, Antoniana U. Krettli
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320718301040