Pre- and postsynaptic changes in the neuromuscular junction in dystrophic mice

Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease in which weakness, increased susceptibility to muscle injury, and inadequate repair appear to underlie the pathology. While most attention has focused within the muscle fiber, we recently demonstrated in mdx mice (murine model...

Full description

Bibliographic Details
Main Authors: Stephen J.P. Pratt, Ana P. Valencia, Gloribel K. Le, Sameer B Shah, Richard M Lovering
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Physiology
Subjects:
mdx
NMJ
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00252/full