UBQLN4 promotes progression of HCC via activating wnt-β-catenin pathway and is regulated by miR-370

Abstract Background Ubiquilin-4 (UBQLN4) is a member of the ubiquitin–proteasome system that is usually upregulated in many tumor cells. Its overexpression has been associated with poor disease outcomes in various cancer diseases. However, the underlying mechanism of UBQLN4 in the development of hep...

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Bibliographic Details
Main Authors: Yan Yu, Penglin Xu, Guangying Cui, Xiaodong Xu, Kongfei Li, Xiaolong Chen, Jie Bao
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-019-1078-5