Survivin Splice Variants in Arsenic Trioxide (As2O3)-Induced Deactivation of PI3K and MAPK Cell Signalling Pathways in MCF-7 Cells

Several pathways are deregulated during carcinogenesis but most notably, tumour cells can lose cell cycle control and acquire resistance to apoptosis by expressing a number of anti-apoptotic proteins such as the Inhibitors of Apoptosis Protein (IAP) family of proteins that include survivin, which is...

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Bibliographic Details
Main Authors: Kagiso Laka, Lilian Makgoo, Zukile Mbita
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/10/1/41