Autologous transplantation of thecal stem cells restores ovarian function in nonhuman primates

Abstract Premature ovarian insufficiency (POI) is defined as the loss of ovarian activity under the age of 40. Theca cells (TCs) play a vital role during folliculogenesis and TCs dysfunction participate in the pathogenesis of POI. Therefore, transplantation of thecal stem cells (TSCs), which are cap...

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Bibliographic Details
Main Authors: Hong Chen, Kai Xia, Weijun Huang, Huijian Li, Chao Wang, Yuanchen Ma, Jianhui Chen, Peng Luo, Shuwei Zheng, Jiancheng Wang, Yi Wang, Lin Dong, Zhipeng Tan, Xingqiang Lai, Frank Fuxiang Mao, Weiqiang Li, Xiaoyan Liang, Tao Wang, Andy Peng Xiang, Qiong Ke
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-021-00291-0