Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis

Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis

Phospholipid scramblase 1 (PLSCR1), a lipid-binding and Ca<sup>2+</sup>-sensitive protein located on plasma membranes, is critically involved in phosphatidylserine (PS) externalization, an important process in cell apoptosis. Transient receptor potential canonical 5 (TRPC5), is a nonsele...

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Bibliographic Details
Main Authors: Jizheng Guo, Jie Li, Lin Xia, Yang Wang, Jinhang Zhu, Juan Du, Yungang Lu, Guodong Liu, Xiaoqiang Yao, Bing Shen
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
apoptosis
cerebral ischemia reperfusion
plscr1
phosphatidylserine
scramblase
trpc5
Online Access:https://www.mdpi.com/2073-4409/9/3/547

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https://www.mdpi.com/2073-4409/9/3/547

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