A Direct Role for the CD1b Endogenous Spacer in the Recognition of a Mycobacterium tuberculosis Antigen by T-Cell Receptors
Lipids, glycolipids and lipopeptides derived from Mycobacterium tuberculosis (Mtb) are presented to T cells by monomorphic molecules known as CD1. This is the case of the Mtb-specific sulfoglycolipid Ac2SGL, which is presented by CD1b molecules and is recognized by T cells found in tuberculosis (TB)...
Main Authors: | Frank Camacho, Ernesto Moreno, Luis F. Garcia-Alles, Glay Chinea Santiago, Martine Gilleron, Aleikar Vasquez, Yee Siew Choong, Fátima Reyes, Mohd Nor Norazmi, Maria E. Sarmiento, Armando Acosta |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2020.566710/full |
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