Lacosamide Reduces Seizure Severity but Increases Seizure Frequency in PTZ-Kindled Rats
Objective: This study evaluated the anticonvulsant action of lacosamide (LCS), a novel drug that was recently approved for the treatment of partial or secondarily generalized seizures, using an animal model of generalized epilepsy induced by repetitive pentylenetetrazole (PTZ) administration in rats...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2017-12-01
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| Series: | Acta Medica Marisiensis |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/amma-2017-0037 |