Multi-site tumor sampling (MSTS) improves the performance of histological detection of intratumor heterogeneity in clear cell renal cell carcinoma (CCRCC) [version 2; referees: 5 approved]

Current standard-of-care tumor sampling protocols for CCRCC (and other cancers) are not efficient at detecting intratumoural heterogeneity (ITH). We have demonstrated in silico that an alternative protocol, multi-site tumor sampling (MSTS) based upon the divide and conquer (DAC) algorithm, can signi...

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Bibliographic Details
Main Authors: Rosa Guarch, Jesús M. Cortés, Charles H. Lawrie, José I. López
Format: Article
Language:English
Published: F1000 Research Ltd 2016-09-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-2020/v2