Involvement of PU.1 in NFATc1 promoter function in osteoclast development

Involvement of PU.1 in NFATc1 promoter function in osteoclast development

Background: The transcription factors NFATc1 and PU.1 play important roles in osteoclast development. NFATc1 and PU.1 transactivate osteoclast-specific gene expression and a deficiency in NFATc1 or PU.1 genes causes osteopetrosis due to an insufficient development of osteoclasts. However, the existe...

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Bibliographic Details
Main Authors: Kentaro Ishiyama, Takuya Yashiro, Nobuhiro Nakano, Kazumi Kasakura, Ryosuke Miura, Mutsuko Hara, Fumitaka Kawai, Keiko Maeda, Naoto Tamura, Ko Okumura, Hideoki Ogawa, Yoshinari Takasaki, Chiharu Nishiyama
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Allergology International
Subjects:
NFATc1
Osteoclasts
Promoter
PU.1
Transcription factor
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015000684

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http://www.sciencedirect.com/science/article/pii/S1323893015000684

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