Predictive Value of High ICAM-1 Level for Poor Treatment Response to Low-Dose Decitabine in Adult Corticosteroid Resistant ITP Patients

Predictive Value of High ICAM-1 Level for Poor Treatment Response to Low-Dose Decitabine in Adult Corticosteroid Resistant ITP Patients

Primary immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease. Endothelial cell activation/injury has been found in some autoimmune diseases including SLE, systemic sclerosis, and rheumatoid arthritis, but its role in ITP pathogenesis remains unclear. This study attempted to elucidate t...

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Bibliographic Details
Main Authors: Chaoyang Li, Lizhen Li, Meng Sun, Jianzhi Sun, Linlin Shao, Miao Xu, Yu Hou, Jun Peng, Lin Wang, Ming Hou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
ICAM-1
immune thrombocytopenia
decitabine
endothelia cell dysfunction
predict
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.689663/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.689663/full

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