Integrated Omics Strategy Reveals Cyclic Lipopeptides Empedopeptins from <i>Massilia</i> sp. YMA4 and Their Biosynthetic Pathway

Integrated Omics Strategy Reveals Cyclic Lipopeptides Empedopeptins from <i>Massilia</i> sp. YMA4 and Their Biosynthetic Pathway

Empedopeptins—eight amino acid cyclic lipopeptides—are calcium-dependent antibiotics that act against Gram-positive bacteria such as <i>Staphylococcus aureus</i> by inhibiting cell wall biosynthesis. However, to date, the biosynthetic mechanism of the empedopeptins has not been well iden...

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Bibliographic Details
Main Authors: Shang-Tse Ho, Ying-Ning Ho, Chih Lin, Wei-Chen Hsu, Han-Jung Lee, Chia-Chi Peng, Han-Tan Cheng, Yu-Liang Yang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Marine Drugs
Subjects:
<i>Massilia</i>
lipopeptides
biosynthesis
genome mining
metabolomics
Online Access:https://www.mdpi.com/1660-3397/19/4/209

Internet

https://www.mdpi.com/1660-3397/19/4/209

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