Comparative genomic and transcriptomic analyses of LNCaP and C4-2B prostate cancer cell lines.

Comparative genomic and transcriptomic analyses of LNCaP and C4-2B prostate cancer cell lines.

The LNCaP and C4-2B cell lines form an excellent preclinical model to study the development of metastatic castration-resistant prostate cancer, since C4-2B cells were derived from a bone metastasis that grew in nude mice after inoculation with the LNCaP-derived, castration-resistant C4-2 cells. Exom...

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Bibliographic Details
Main Authors: Lien Spans, Christine Helsen, Liesbeth Clinckemalie, Thomas Van den Broeck, Stefan Prekovic, Steven Joniau, Evelyne Lerut, Frank Claessens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3938550?pdf=render

Internet

http://europepmc.org/articles/PMC3938550?pdf=render

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