Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection

Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection

Abstract Background Pichia pastoris (syn. Komagataella phaffii) is one of the most highly utilized eukaryotic expression systems for the production of heterologous glycoproteins, being able to perform both N- and O-mannosylation. In this study, we present the expression in P. pastoris of an O-mannos...

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Bibliographic Details
Main Authors: Giroshi Bando-Campos, Daniel Juárez-López, Sergio A. Román-González, Antonia I. Castillo-Rodal, Clarita Olvera, Yolanda López-Vidal, Roberto Arreguín-Espinosa, Clara Espitia, Mauricio A. Trujillo-Roldán, Norma A. Valdez-Cruz
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Microbial Cell Factories
Subjects:
Mycobacterium tuberculosis
Antigen
Glycoprotein
Pichia pastoris
PstS-1
O-mannosylation
Online Access:http://link.springer.com/article/10.1186/s12934-019-1059-3

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http://link.springer.com/article/10.1186/s12934-019-1059-3

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