Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons.

Obesity is one of the largest health problems facing the world today. Although twin and family studies suggest about two-thirds of obesity is caused by genetic factors, only a small fraction of this variance has been unraveled. There are still large numbers of genes to be identified that cause varia...

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Main Authors: Zhe Zhang, Chan-Juan Hao, Chang-Gui Li, Dong-Jie Zang, Jing Zhao, Xiao-Nan Li, Ai-Hua Wei, Zong-Bo Wei, Lin Yang, Xin He, Xue-Chu Zhen, Xiang Gao, John R Speakman, Wei Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3923682?pdf=render