Comparing sensitivity to change using the 6-item versus the 17-item Hamilton depression rating scale in the GUIDED randomized controlled trial

Comparing sensitivity to change using the 6-item versus the 17-item Hamilton depression rating scale in the GUIDED randomized controlled trial

Abstract Background Previous research suggests that the 17-item Hamilton Depression Rating Scale (HAM-D17) is less sensitive in detecting differences between active treatment and placebo for major depressive disorder (MDD) than is the HAM-D6 scale, which focuses on six core depression symptoms. Whet...

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Bibliographic Details
Main Authors: Boadie W. Dunlop, Sagar V. Parikh, Anthony J. Rothschild, Michael E. Thase, Charles DeBattista, Charles R. Conway, Brent P. Forester, Francis M. Mondimore, Richard C. Shelton, Matthew Macaluso, Jennifer Logan, Paul Traxler, James Li, Holly Johnson, John F. Greden
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Psychiatry
Subjects:
Genetics
Antidepressant
Depression
Biomarker
Pharmacogenomics
Clinical trial
Online Access:https://doi.org/10.1186/s12888-019-2410-2

Internet

https://doi.org/10.1186/s12888-019-2410-2

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