Establishment of a Bovine Viral Diarrhea Virus Type 2 Intranasal Challenge Model for Assessing Vaccine Efficacy

Establishment of a Bovine Viral Diarrhea Virus Type 2 Intranasal Challenge Model for Assessing Vaccine Efficacy

The objective of this study was to develop a bovine viral diarrhea virus type 2 (BVDV-2) challenge model suitable for evaluation of efficacy of BVDV vaccines; a model that mimics natural infection and induces clear leukopenia and viremia. Clinical, hematological and virological parameters were evalu...

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Bibliographic Details
Main Authors: Rebecca Strong, Simon P. Graham, S. A. La Rocca, Rudiger Raue, Ilse Vangeel, Falko Steinbach
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Veterinary Science
Subjects:
bovine viral diarrhea virus type 2
experimental infection
pathogenesis
virus persistence
challenge model
Online Access:http://journal.frontiersin.org/article/10.3389/fvets.2018.00024/full

Internet

http://journal.frontiersin.org/article/10.3389/fvets.2018.00024/full

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