Thioredoxin-interacting protein regulates glucose metabolism and affects cytoplasmic streaming in mouse oocytes.

Thioredoxin-interacting protein (Txnip) regulates intracellular redox state and prompts oxidative stress by binding to and inhibiting Thioredoxin (Trx). In addition, via a Trx-independent mechanism, Txnip regulates glucose metabolism and thus maintains intracellular glucose levels. Previously, we fo...

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Bibliographic Details
Main Authors: Su-Yeon Lee, Hyun-Seo Lee, Eun-Young Kim, Jung-Jae Ko, Tae Ki Yoon, Woo-Sik Lee, Kyung-Ah Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3747264?pdf=render