Development of Plant Prime-Editing Systems for Precise Genome Editing

Prime-editing systems have the capability to perform efficient and precise genome editing in human cells. In this study, we first developed a plant prime editor 2 (pPE2) system and test its activity by generating a targeted mutation on an HPT-ATG reporter in rice. Our results showed that the pPE2 sy...

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Bibliographic Details
Main Authors: Rongfang Xu, Juan Li, Xiaoshuang Liu, Tiaofeng Shan, Ruiying Qin, Pengcheng Wei
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Plant Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590346220300262