CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells.

Malignant pleural mesothelioma (MPM) is an asbestos-related thoracic malignancy that is characterized by late metastases, and resistance to therapeutic modalities. The toxic side-effects of MPM therapies often limit their clinical effectiveness, thus necessitating development of new agents to effect...

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Bibliographic Details
Main Authors: Shazia Jamal, Vino T Cheriyan, Magesh Muthu, Sara Munie, Edi Levi, Abdelkader E Ashour, Harvey I Pass, Anil Wali, Mandip Singh, Arun K Rishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24598827/pdf/?tool=EBI