Estrogen regulation of anti-apoptotic Bcl-2 family member Mcl-1 expression in breast cancer cells.

Estrogen is implicated as an important factor in stimulating breast cancer cell proliferation, and presence of estrogen receptor (ER) is an indication of a good prognosis in breast cancer patients. Mcl-1 is an anti-apoptotic Bcl-2 family member that is often over expressed in breast tumors, correlat...

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Bibliographic Details
Main Authors: Jennifer L Schacter, Elizabeth S Henson, Spencer B Gibson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4074091?pdf=render