Tyrosine Kinase c-MET as Therapeutic Target for Radiosensitization of Head and Neck Squamous Cell Carcinomas

Tyrosine Kinase c-MET as Therapeutic Target for Radiosensitization of Head and Neck Squamous Cell Carcinomas

The receptor tyrosine kinase c-MET activates intracellular signaling and induces cell proliferation, epithelial-to-mesenchymal-transition and migration. Within the present study, we validated the prognostic value of c-MET in patients with head and neck squamous cell carcinoma (HNSCC) treated with ra...

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Bibliographic Details
Main Authors: Lina Lüttich, María José Besso, Stephan Heiden, Lydia Koi, Michael Baumann, Mechthild Krause, Anna Dubrovska, Annett Linge, Ina Kurth, Claudia Peitzsch
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
radiotherapy
cancer stem cells
c-MET kinase signaling
head and neck squamous cell carcinoma
resistance
Online Access:https://www.mdpi.com/2072-6694/13/8/1865

Internet

https://www.mdpi.com/2072-6694/13/8/1865

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