Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden.

Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate infection-associated morbidity. Murine resistin-like...

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Bibliographic Details
Main Authors: Jessica C Jang, Gang Chen, Spencer H Wang, Mark A Barnes, Josiah I Chung, Mali Camberis, Graham Le Gros, Philip J Cooper, Cathy Steel, Thomas B Nutman, Mitchell A Lazar, Meera G Nair
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004579