Mycobacterium tuberculosis induces decelerated bioenergetic metabolism in human macrophages

Mycobacterium tuberculosis induces decelerated bioenergetic metabolism in human macrophages

How Mycobacterium tuberculosis (Mtb) rewires macrophage energy metabolism to facilitate survival is poorly characterized. Here, we used extracellular flux analysis to simultaneously measure the rates of glycolysis and respiration in real time. Mtb infection induced a quiescent energy phenotype in hu...

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Bibliographic Details
Main Authors: Bridgette M Cumming, Kelvin W Addicott, John H Adamson, Adrie JC Steyn
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-11-01
Series:eLife
Subjects:
Mycobacterium tuberculosis
macrophages
bioenergetic metabolism
extracellular flux analysis
Mycobacterium bovis BCG
Online Access:https://elifesciences.org/articles/39169

Internet

https://elifesciences.org/articles/39169

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