Oenothein B Suppresses Lipopolysaccharide (LPS)-Induced Inflammation in the Mouse Brain

Oenothein B Suppresses Lipopolysaccharide (LPS)-Induced Inflammation in the Mouse Brain

Oenothein B has been recently evaluated for its ability to affect inflammatory responses in peripheral tissues. In this study, we examined its effect on the damage to the central nervous system due to systemic inflammation. For this purpose, ICR mice were injected with an intraperitoneal (i.p.) dose...

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Bibliographic Details
Main Authors: Yoshiko Furukawa, Mitsunari Nakajima, Takashi Yoshida, Yoshiaki Amakura, Morio Yoshimura, Nahomi Makihata, Satoshi Okuyama
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:International Journal of Molecular Sciences
Subjects:
oenothein B
lipopolysaccharide
depression-like behavior
hippocampus
inflammation
microglia
COX-2
astrocyte
Online Access:http://www.mdpi.com/1422-0067/14/5/9767

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http://www.mdpi.com/1422-0067/14/5/9767

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