Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons

Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons

Summary: The Piwi-interacting RNA (piRNA) pathway safeguards genomic integrity by silencing transposable elements (transposons) in the germline. While Piwi is the central piRNA factor, others including Asterix/Gtsf1 have also been demonstrated to be critical for effective silencing. Here, using enha...

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Bibliographic Details
Main Authors: Jonathan J. Ipsaro, Paul A. O’Brien, Shibani Bhattacharya, Arthur G. Palmer, III, Leemor Joshua-Tor
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
Asterix
Gtsf1
RNA
tRNA
piRNA
LTR
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472100228X

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http://www.sciencedirect.com/science/article/pii/S221112472100228X

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