Recent developments on PET radiotracers for TSPO and their applications in neuroimaging

Recent developments on PET radiotracers for TSPO and their applications in neuroimaging

The 18 kDa translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor, is predominately localized to the outer mitochondrial membrane in steroidogenic cells. Brain TSPO expression is relatively low under physiological conditions, but is upregulated in response to glial c...

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Bibliographic Details
Main Authors: Lingling Zhang, Kuan Hu, Tuo Shao, Lu Hou, Shaojuan Zhang, Weijian Ye, Lee Josephson, Jeffrey H. Meyer, Ming-Rong Zhang, Neil Vasdev, Jinghao Wang, Hao Xu, Lu Wang, Steven H. Liang
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
TSPO
Microglial activation
Neuroinflammation
Positron emission tomography (PET)
CNS disorders
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383520306894

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http://www.sciencedirect.com/science/article/pii/S2211383520306894

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