Z-DNA-Binding Protein 1 Is Critical for Controlling Virus Replication and Survival in West Nile Virus Encephalitis

Z-DNA-Binding Protein 1 Is Critical for Controlling Virus Replication and Survival in West Nile Virus Encephalitis

West Nile virus (WNV), a neurotropic flavivirus, is the leading cause of viral encephalitis in the United States. Recently, Zika virus (ZIKV) infections have caused serious neurological diseases and birth defects, specifically Guillain-Barrè syndrome and microcephaly. Z-DNA binding protein 1 (ZBP1)...

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Bibliographic Details
Main Authors: Hussin A. Rothan, Komal Arora, Janhavi P. Natekar, Philip G. Strate, Margo A. Brinton, Mukesh Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
West Nile virus
flavivirus
Zika virus
Z-DNA-binding protein 1
DNA-dependent activator of IFN-regulatory factors
host-pathogen interaction
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02089/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02089/full

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