Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer.

Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer.

Reports demonstrate the role of M-CSF (CSF1) in tumor progression in mouse models as well as the prognostic value of macrophage numbers in breast cancer patients. Recently, a subset of CD14+ monocytes expressing the Tie2 receptor, once thought to be predominantly expressed on endothelial cells, has...

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Bibliographic Details
Main Authors: Mary A Forget, Jeffrey L Voorhees, Sara L Cole, Duaa Dakhlallah, Ivory L Patterson, Amy C Gross, Leni Moldovan, Xiaokui Mo, Randall Evans, Clay B Marsh, Tim D Eubank
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4043882?pdf=render

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http://europepmc.org/articles/PMC4043882?pdf=render

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